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Histopathological and epidemiological characteristics of patients with erythema exudativum multiforme major, Stevens-Johnson syndrome and toxic epidermal necrolysis. Affected patients have severe pruritus and peripheral eosinophilia. Sep 1, Issue. It is caused by a deficiency in uroporphyrinogen decarboxylase, leading to the accumulation of uroporphyrin in the urine and serum.
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The Generalized Rash: Part I. Differential Diagnosis

Penis pink macules or plaque
Penis pink macules or plaque
Penis pink macules or plaque
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Erythematous penile lesion | MDedge Family Medicine

Pseudoporphyria mimics porphyria cutanea tarda without an enzyme defect; plasma and urinary porphyrins are normal. Cayenne pepper spots are characteristic. Part I of this two-part article focuses on differential diagnosis of generalized rashes. Treatment for types II and III includes weight loss and treatment of the underlying endocrine disorder, if applicable. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference.
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Pruritic Erythematous Plaques

When inherited, acrodermatitis enteropathica results from a mutation in SLC39A, which encodes an intestinal zinc transporter. Mar 15, Issue. Asymmetric, reddish patches and plaques; often misdiagnosed early on as other benign skin conditions, such as eczema and psoriasis.
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Acanthosis nigricans can develop following the use of some medications, such as systemic corticosteroids, nicotinic acid, diethylstilbestrol, and isoniazid INH. The eruption presents with the same target-shaped lesions seen in EM minor but is accompanied by systemic symptoms and mucosal involvement. Differential diagnosis includes erythema multiforme, deep fungal infection, pyoderma gangrenosum, and cutaneous metastases. Stanley JR. You must see it mmd r 18 ibrs bgs demon
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